(R_P,R_P)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane

Base Information

• Chemical Name: (R_P,R_P)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane
• CAS No.: 917029-48-2
• Molecular Formula: C₃₀H₃₄B₂O₄P₂
• Molecular Weight: 542.167
• Mol file: 917029-48-2.mol

Synonyms:(R_P,R_P)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane

Chemical Property of (R_P,R_P)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R_P,R_P)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane

There total 4 articles about (R_P,R_P)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(RP,RP)-1,2-bis[(o-hydroxyphenyl)(phenyl)phosphino-P-borane]ethane (1316041-04-9,917029-15-3) + acetyl chloride (75-36-5) → (RP,RP)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane (917029-48-2)

Guidance literature:

(R_P,R_P)-1,2-bis[(o-hydroxyphenyl)(phenyl)phosphino-P-borane]ethane; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

acetyl chloride; In tetrahydrofuran; for 1h; Inert atmosphere;

DOI:10.1039/c1ob05364g

Reference yield:

(RP,RP)-1,2-bis[(o-anisyl)(phenyl)phosphino-P-borane]ethane (131830-91-6,136844-63-8,162490-91-7,97764-56-2) → (RP,RP)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane (917029-48-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: diethylamine / Reflux; Inert atmosphere

2.1: boron tribromide / dichloromethane / 1 h / -20 - 20 °C / Inert atmosphere

2.2: 0 °C / Reflux; Inert atmosphere

3.1: borane-dimethyl sulfide complex / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

4.1: sodium hydride / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

4.2: 1 h / Inert atmosphere

With borane-dimethyl sulfide complex; boron tribromide; sodium hydride; diethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c1ob05364g

Reference yield:

(RP,RP)-1,2-bis[(o-anisyl)(phenyl)phosphino]ethane (55739-58-7,63449-62-7,63589-61-7,97858-62-3) → (RP,RP)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino-P-borane]ethane (917029-48-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: boron tribromide / dichloromethane / 1 h / -20 - 20 °C / Inert atmosphere

1.2: 0 °C / Reflux; Inert atmosphere

2.1: borane-dimethyl sulfide complex / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

3.2: 1 h / Inert atmosphere

With borane-dimethyl sulfide complex; boron tribromide; sodium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c1ob05364g

upstream raw materials:

(R_P,R_P)-1,2-bis[(o-hydroxyphenyl)(phenyl)phosphino-P-borane]ethane

acetyl chloride

(R_P,R_P)-1,2-bis[(o-anisyl)(phenyl)phosphino-P-borane]ethane

(R_P,R_P)-1,2-bis[(o-hydroxyphenyl)(phenyl)phosphino]ethane

Downstream raw materials:

(R_P,R_P)-1,2-bis[(2-acetoxyphenyl)(phenyl)phosphino]ethane