4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl]-2-fluorobenzoic acid

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Chemical Name:4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl]-2-fluorobenzoic acid
CAS No.:1242145-12-5
Molecular Formula:C₂₂H₁₉ClFN₃O₂
Molecular Weight:411.863
Hs Code.:

Synonyms:4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl]-2-fluorobenzoic acid

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Chemical Property of 4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl]-2-fluorobenzoic acid

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Technology Process of 4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl]-2-fluorobenzoic acid

There total 1 articles about 4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl]-2-fluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 120153-08-4
4-(dihydroxyboranyl)-2-fluorobenzoic acid

: 1242145-41-0
2-chloro-4-[(5R)-3-chloro-5-cyclopentyl-4,5-dihydro-1H-pyrazol-1-yl]benzonitrile

: 1242145-12-5
4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl]-2-fluorobenzoic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In N,N-dimethyl-formamide; at 85 ℃; for 8h; Inert atmosphere;
DOI:10.1021/jm100505n