N-(4-methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

Base Information

Chemical Name:N-(4-methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
CAS No.:864754-46-1
Molecular Formula:C19H23 B N2 O3
Molecular Weight:338.214
Hs Code.:
DSSTox Substance ID:DTXSID10592305
Wikidata:Q82486351
Mol file:864754-46-1.mol

Synonyms:864754-46-1;N-(4-methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide;Benzamide,N-(4-methyl-2-pyridinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;starbld0019378;N-(4-METHYL-PYRIDIN-2-YL)-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZAMIDE;SCHEMBL14630208;DTXSID10592305;SRNLWGKIMGETIM-UHFFFAOYSA-N;SB83396;N-(4-Methyl-2-pyridinyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamide;DB-361142;A1-05995;N-(4-Methyl-2-pyridinyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide;N-(4-methyl-pyridin-2-yl)-4-(4,4,5,5-tetramethyl -[1,3,2]dioxaborolan-2-yl)-benzamide

Suppliers and Price of N-(4-methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
N-(4-Methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
2.500g
$ 1320.00

American Custom Chemicals Corporation
N-(4-METHYL-PYRIDIN-2-YL)-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZAMIDE 95.00%
5MG
$ 503.28

A1 Biochem Labs
N-(4-Methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 95%
2.5 g
$ 800.00

Total 2 raw suppliers

Chemical Property of N-(4-methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

Chemical Property:

PSA：60.45000
LogP:3.01450
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:338.1801728
Heavy Atom Count:25
Complexity:473

Purity/Quality:

99% ^*data from raw suppliers

N-(4-Methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)C(=O)NC3=NC=CC(=C3)C

Technology Process of N-(4-methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

There total 5 articles about N-(4-methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 33115-66-1
4-bromo-N-(4-methylpyridin-2-yl)benzamide

: 73183-34-3
bis(pinacol)diborane

: 864754-46-1
N-(4-(4-methylpyridine)-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In N,N-dimethyl-formamide; at 80 ℃; Inert atmosphere;

Reference yield:

: 180516-87-4
4-carboxyphenylboronic acid pinacol ester

: 864754-46-1
N-(4-(4-methylpyridine)-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 3.5 h / 0 - 20 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 20 °C

2.2: 2.5 h / 20 °C

With oxalyl dichloride; N,N-dimethyl-formamide; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane;

Reference yield:

: 586-76-5
4-Bromobenzoic acid

: 864754-46-1
N-(4-(4-methylpyridine)-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride / toluene / 3 h / Reflux

1.2: 6 h / 20 °C / Cooling with ice; Inert atmosphere

2.1: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / Reflux

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; thionyl chloride; potassium acetate; In 1,4-dioxane; toluene;