methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate

Base Information

Chemical Name:methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate
CAS No.:1337469-43-8
Molecular Formula:C₂₂H₂₉IN₂O₃
Molecular Weight:496.388
Hs Code.:

Synonyms:methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate

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Chemical Property of methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate

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Technology Process of methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate

There total 1 articles about methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1055233-46-9
methyl 6-[N-ethyl-N-(3-isobutoxy-4-isopropylphenyl)amino]nicotinate

: 1337469-43-8
methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate

Guidance literature:: With iodine; silver sulfate; In methanol; at 20 ℃; for 11h;
DOI:10.1021/ml200197e

Reference yield: 97.0%

: 100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6
styrene

: 1337469-43-8
methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate

: 1337469-42-7
C₃₀H₃₆N₂O₃

Guidance literature:: With palladium diacetate; triethylamine; tris-(o-tolyl)phosphine; In acetonitrile; at 110 ℃; for 72h; Inert atmosphere;
DOI:10.1021/ml200197e

Reference yield: 85.0%

: 1337469-43-8
methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate

: 1337469-46-1
6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinic acid

Guidance literature:: methyl 6-[N-ethyl-N-(2-iodo-5-isobutoxy-4-isopropylphenyl)amino]nicotinate; With sodium hydroxide; In methanol; at 60 ℃; for 1h;

With hydrogenchloride; In methanol; water;
DOI:10.1021/ml200197e