Dimethylenastron

Base Information

Chemical Name:Dimethylenastron
CAS No.:863774-58-7
Molecular Formula:C16H18 N2 O2 S
Molecular Weight:302.397
Hs Code.:
European Community (EC) Number:878-595-9
ChEMBL ID:CHEMBL394880
DSSTox Substance ID:DTXSID40469410
Pharos Ligand ID:U1YA1HT4XF9F
Mol file:863774-58-7.mol

Synonyms:dimethylenastron;DMEN enastron

Suppliers and Price of Dimethylenastron

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Dimethylenastron
10mg
$ 438.00

Tocris
Dimethylenastron ≥99%(HPLC)
50
$ 604.00

Tocris
Dimethylenastron ≥99%(HPLC)
10
$ 146.00

Sigma-Aldrich
Eg5 Inhibitor III, Dimethylenastron
5mg
$ 325.60

Sigma-Aldrich
Dimethylenastron ≥98% (HPLC)
25mg
$ 386.00

Sigma-Aldrich
Eg5 Inhibitor III, Dimethylenastron
1mg
$ 119.32

Sigma-Aldrich
Dimethylenastron ≥98% (HPLC)
5mg
$ 102.00

DC Chemicals
Eg5 Inhibitor III, Dimethylenastron >98%
250 mg
$ 900.00

Crysdot
Dimethylenastron 98+%
50mg
$ 498.00

Crysdot
Dimethylenastron 98+%
100mg
$ 789.00

Total 19 raw suppliers

Chemical Property of Dimethylenastron

Chemical Property:

Boiling Point:475.6±55.0 °C(Predicted)
PKA:9.59±0.10(Predicted)
PSA：93.45000
Density:1.34±0.1 g/cm3(Predicted)
LogP:3.21180
Storage Temp.:2-8°C
Solubility.:DMSO: soluble15mg/mL, clear
XLogP3:2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:302.10889899
Heavy Atom Count:21
Complexity:512

Purity/Quality:

99%, ^*data from raw suppliers

Dimethylenastron ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC2=C(C(NC(=S)N2)C3=CC(=CC=C3)O)C(=O)C1)C
Uses Dimethylnasetron is an inhibitor of mitotic motor kinesin Eg5, triggering apoptosis and upregulates Hsp-70 in human myeloma cells.

Technology Process of Dimethylenastron

There total 2 articles about Dimethylenastron which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%