Technology Process of ethyl 3-(4-methylphenyl)hex-5-enoate
There total 3 articles about ethyl 3-(4-methylphenyl)hex-5-enoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
water; sodium chloride;
In
dimethyl sulfoxide;
at 170 ℃;
for 0.5h;
Microwave irradiation;
DOI:10.1021/jo200268e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: piperidine; acetic acid / toluene / Dean-Stark
2.1: ytterbium(III) trifluoromethanesulfonate hydrate; 1,1,1,3',3',3'-hexafluoro-propanol / dichloromethane / 0.17 h / 20 °C
2.2: 18 h / 20 °C
3.1: water; sodium chloride / dimethyl sulfoxide / 0.5 h / 170 °C / Microwave irradiation
With
piperidine; ytterbium(III) trifluoromethanesulfonate hydrate; 1,1,1,3',3',3'-hexafluoro-propanol; water; acetic acid; sodium chloride;
In
dichloromethane; dimethyl sulfoxide; toluene;
1.1: Knoevenagel condensation / 3.1: Krapcho decarboalkoxylation;
DOI:10.1021/jo200268e
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: ytterbium(III) trifluoromethanesulfonate hydrate; 1,1,1,3',3',3'-hexafluoro-propanol / dichloromethane / 0.17 h / 20 °C
1.2: 18 h / 20 °C
2.1: water; sodium chloride / dimethyl sulfoxide / 0.5 h / 170 °C / Microwave irradiation
With
ytterbium(III) trifluoromethanesulfonate hydrate; 1,1,1,3',3',3'-hexafluoro-propanol; water; sodium chloride;
In
dichloromethane; dimethyl sulfoxide;
2.1: Krapcho decarboalkoxylation;
DOI:10.1021/jo200268e
![diethyl 2-[1-(4-methylphenyl)but-3-enyl]malonate](/Databaselist/images/loading.webp)
