pyridine-2,6-diylbis(ethene-2,1-diylbenzene-4,1-diyl) diacetate

Base Information

• Chemical Name: pyridine-2,6-diylbis(ethene-2,1-diylbenzene-4,1-diyl) diacetate
• CAS No.: 94356-50-0
• Molecular Formula: C25H21 N O4
• Molecular Weight: 399.446
• Mol file: 94356-50-0.mol

Synonyms:NSC 31607

Chemical Property of pyridine-2,6-diylbis(ethene-2,1-diylbenzene-4,1-diyl) diacetate

Chemical Property:

• Vapor Pressure: 7.7E-13mmHg at 25°C
• Boiling Point: 566.2°C at 760 mmHg
• Flash Point: 296.2°C
• Density: 1.231g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of pyridine-2,6-diylbis(ethene-2,1-diylbenzene-4,1-diyl) diacetate

There total 2 articles about pyridine-2,6-diylbis(ethene-2,1-diylbenzene-4,1-diyl) diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2,6-dimethylpyridine (108-48-5) + acetic anhydride (108-24-7) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 2,6-bis-[2-(4-ethanoyloxyphenyl)ethenyl]pyridine (94356-50-0)

Guidance literature:

for 24h; Reflux;

DOI:10.1039/c6nj01515h

Reference yield:

2,6-dimethylpyridine (108-48-5) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 2,6-bis-(4-acetoxy-trans-styryl)-pyridine (94356-50-0)

Guidance literature:

With acetic anhydride;

DOI:10.1021/ja01145a085 DOI:10.1021/jo01152a010

Reference yield: 32.0%

2,6-bis-[2-(4-ethanoyloxyphenyl)ethenyl]pyridine (94356-50-0) → 2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine (1241-14-1)

Guidance literature:

With potassium hydroxide; In ethanol; for 1.5h; Reflux;

DOI:10.1039/c3nj01430d

upstream raw materials:

2,6-dimethylpyridine

4-hydroxy-benzaldehyde

acetic anhydride

Downstream raw materials:

2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine

2,6-bis-(4-hydroxy-phenethyl)-pyridine

2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine

Refernces

• 1、 Joolakanti, Shyamsunder R.,Nickell, Justin R.,Janganati, Venumadhav,Zheng, Guangrong,Dwoskin, Linda P.,Crooks, Peter A.. "Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [3H]dopamine uptake at the vesicular monoamine transporter-2". . p. 2422 - 2427. Retrieved 2016/07/07.
• 2、 Markovi?,Tri?ovi?,Tóth-Katona,Mil?i?,Marinkovi?,Zhang,Jákli,Fodor-Csorba. "A structure-property relationship study of bent-core mesogens with pyridine as the central unit". . p. 1751 - 1760. Retrieved 2014/05/06.