1241-14-1

Basic information

• Product Name: 2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine
• Synonyms: 2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine
• CAS NO: 1241-14-1
• Molecular Weight: 315.371
• Mol File: 1241-14-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine(1241-14-1)
• EPA Substance Registry System: 2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine(1241-14-1)

Safety Data

• Hazardous Substances Data: 1241-14-1(Hazardous Substances Data)

Upstream product

• 94356-50-0 2,6-bis-(4-acetoxy-trans-styryl)-pyridine 
• 108-48-5 2,6-dimethylpyridine 
• 123-08-0 4-hydroxy-benzaldehyde 
• 94356-50-0 2,6-bis-[2-(4-ethanoyloxyphenyl)ethenyl]pyridine 
• 6266-89-3 2,6-bis-(4-methoxy-trans-styryl)-pyridine 

Downstream Products

• 857940-47-7 Acetic acid 4-(2-{(2R,6S)-6-[2-(4-acetoxy-phenyl)-ethyl]-piperidin-2-yl}-ethyl)-phenyl ester 

Relevant articles and documents

Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [3H]dopamine uptake at the vesicular monoamine transporter-2

A series of lobelane and GZ-793A analogues that incorporate aromatic 4-hydroxy and 4-(2-fluoroethoxy) substituents were synthesized and evaluated for inhibition of [3H]dopamine (DA) uptake at the vesicular monoamine transporter-2 (VMAT2) and th

Investigation of supramolecular architectures of bent-shaped pyridine derivatives: From a three-ring crystalline compound towards five-ring mesogens

In search of novel photoactive liquid crystals, we have synthesized a series of five-ring pyridine-based bent-core compounds bearing different substituents at the peripheral phenyl rings (CH3O, Cl and NO2). Their mesomorphic behaviour has been investigated by polarizing optical microscopy, differential scanning calorimetry and X-ray scattering, and then compared with the unsubstituted parent compound. The introduction of the methoxy groups at the peripheral phenyl rings of the bent core results in a non-mesomorphic compound, whereas the chloro- and nitro-substituted compounds form enantiotropic B1-like phases. Significant changes in the textures and transition temperatures of the mesophase have been observed under UV light. The present investigation of the mesomorphic properties of the synthesized compounds, coupled with the analysis of the molecular packing of the related three-ring compounds, will help design self-organized molecules suitable for UV indicators.

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2

A series of lobelane analogues has been synthesized and their structure-activity relationships at the vesicular monoamine transporter-2 (VMAT2) have been evaluated. The most potent analogues in this series were the cis-2,6-piperidino analogues, 25b, 27b, 28b, and 30b, with Ki values ranging from 430 to 580 nM.