(3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid

Base Information

• Chemical Name: (3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid
• CAS No.: 174623-90-6
• Molecular Formula: C₂₂H₂₇NO₆
• Molecular Weight: 401.459
• Mol file: 174623-90-6.mol

Synonyms:(3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid

Chemical Property of (3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid

There total 26 articles about (3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

((1S,2R)-1-Benzyl-2-methoxymethoxy-4-oxo-butyl)-methyl-carbamic acid benzyl ester → (3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid (174623-90-6)

Guidance literature:

With potassium permanganate; disodium hydrogenphosphate; In water; tert-butyl alcohol; at 20 ℃;

DOI:10.1016/S0040-4039(99)01953-X

Reference yield: 90.0%

(4S,3R)-4-(benzyloxycarbonyl-methylamino)-3-methoxymethoxy-5-phenyl-pentanoic acid ethyl ester (236749-56-7) → (3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid (174623-90-6)

Guidance literature:

With potassium carbonate; In methanol; Heating;

DOI:10.1016/0040-4039(96)01415-3

Reference yield: 84.0%

((1S,2R)-1-Benzyl-2-methoxymethoxy-pent-4-enyl)-methyl-carbamic acid benzyl ester (174623-89-3) → (3R,4R)-4-[(benzyloxycarbonyl)(methyl) amino]-3-(methoxymethoxy)-5-phenylpentanoic Acid (174623-90-6)

Guidance literature:

With ruthenium trichloride; sodium periodate; In tetrachloromethane; water; acetonitrile; at 23 ℃;

upstream raw materials:

((1S,2R)-1-Benzyl-2-methoxymethoxy-pent-4-enyl)-methyl-carbamic acid benzyl ester

(4S,3R)-4-(benzyloxycarbonyl-methylamino)-3-methoxymethoxy-5-phenyl-pentanoic acid ethyl ester

methyl iodide

(R,R)-3-(phenylmethyl)oxiranemethanol

Downstream raw materials:

(2S,5S,6R,10R)-5-Benzyl-10-heptyl-2-isopropyl-6-methoxymethoxy-4-methyl-1,9-dioxa-4-aza-cyclododecane-3,8,12-trione