bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate

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Chemical Name:bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate
CAS No.:929281-55-0
Molecular Formula:C₃₄H₃₅ClN₆O₆S
Molecular Weight:691.207
Hs Code.:

Synonyms:bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate

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Chemical Property of bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate

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Technology Process of bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate

There total 1 articles about bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 929281-53-8
bis(1,1-dimethylethyl) (6-iodo-3-pyridazinyl)imidocarbonate

: 929278-56-8
3-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-5-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazol-1-yl]-2-thiophenecarboxamide

: 929281-55-0
bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate

Guidance literature:: With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In N,N-dimethyl acetamide; water; at 80 ℃; for 3h;

Reference yield: 41.0%

: 929281-55-0
bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate

: 5-[5-(6-amino-3-pyridazinyl)-1H-benzimidazol-1-yl]-3-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thiophenecarboxamide

Guidance literature:: bis(1,1-dimethylethyl) {6-[1-(5-(aminocarbonyl)-4-{[(1R)-1-(2-chlorophenyl)ethyl]oxy}-2-thienyl)-1H-benzimidazol-5-yl]-3-pyridazinyl}imidocarbonate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

With sodium hydrogencarbonate; In dichloromethane; water;