(R)-4-(1-hydroxyethyl)-2-methylphenol

Base Information

Chemical Name:(R)-4-(1-hydroxyethyl)-2-methylphenol
CAS No.:1427170-34-0
Molecular Formula:C₉H₁₂O₂
Molecular Weight:152.193
Hs Code.:

Synonyms:(R)-4-(1-hydroxyethyl)-2-methylphenol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-4-(1-hydroxyethyl)-2-methylphenol

Chemical Property:

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Technology Process of (R)-4-(1-hydroxyethyl)-2-methylphenol

There total 2 articles about (R)-4-(1-hydroxyethyl)-2-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 45803-83-6
3-methyl-4-hydroxystyrene

: 1427170-34-0
(R)-4-(1-hydroxyethyl)-2-methylphenol

: 1427170-24-8
(S)-4-(1-hydroxyethyl)-2-methylphenol

Guidance literature:: With hydrobenzoic acid decarboxylase; water; potassium hydrogencarbonate; In aq. buffer; at 30 ℃; for 24h; enantioselective reaction; Enzymatic reaction;
DOI:10.1002/anie.201308556

Reference yield:

: 19780-88-2
4-hydroxy-3-methylcinnamic acid

: 1427170-34-0
(R)-4-(1-hydroxyethyl)-2-methylphenol

: 1427170-24-8
(S)-4-(1-hydroxyethyl)-2-methylphenol

Guidance literature:: Multi-step reaction with 2 steps

1: ferulic acid decarboxylase from Enterobacter sp / isopropyl alcohol; aq. phosphate buffer / 25 °C / pH 6 / Enzymatic reaction

2: ferulic acid decarboxylase from Enterobacter sp. V₄₆E hydratase variant; water / propylene glycol; aq. phosphate buffer / 24 h / 25 °C / pH 6 / Enzymatic reaction

With ferulic acid decarboxylase from Enterobacter sp. V₄₆E hydratase variant; ferulic acid decarboxylase from Enterobacter sp; water; In propylene glycol; aq. phosphate buffer; isopropyl alcohol;
DOI:10.1021/acs.orglett.8b02058