anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine

Base Information

• Chemical Name: anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine
• CAS No.: 89467-16-3
• Molecular Formula: C₂₃H₂₀N₂O
• Molecular Weight: 340.425
• Mol file: 89467-16-3.mol

Synonyms:anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine

Chemical Property of anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine

There total 4 articles about anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methyl-5-(benzoylhydrazino)-5H-dibenzocycloheptene (89442-06-8) → anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine (89467-16-3)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 110 ℃; for 18h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/jo00243a031

Reference yield:

5-hydroxy-5-methyl-5H-dibenzocycloheptene (18259-45-5) → anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine (89467-16-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / dichloroacetic acid / CH₂Cl₂ / 0.5 h / Ambient temperature

2: potassium tert-butoxide / dimethylsulfoxide / 18 h / 110 °C

With dichloro-acetic acid; potassium tert-butylate; In dichloromethane; dimethyl sulfoxide;

DOI:10.1021/jo00243a031

Reference yield:

benzoic acid hydrazide (613-94-5) → anti-12-(benzylamino)-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine (89467-16-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / dichloroacetic acid / CH₂Cl₂ / 0.5 h / Ambient temperature

2: potassium tert-butoxide / dimethylsulfoxide / 18 h / 110 °C

With dichloro-acetic acid; potassium tert-butylate; In dichloromethane; dimethyl sulfoxide;

DOI:10.1021/jo00243a031

upstream raw materials:

5-methyl-5-(benzoylhydrazino)-5H-dibenzocycloheptene

5-hydroxy-5-methyl-5H-dibenzocycloheptene

benzoic acid hydrazide

dibenzosuberenon

Refernces