C₁₈H₂₁N₅O₄S

Base Information

• Chemical Name: C₁₈H₂₁N₅O₄S
• CAS No.: 1539303-95-1
• Molecular Formula: C₁₈H₂₁N₅O₄S
• Molecular Weight: 403.462
• Mol file: 1539303-95-1.mol

Synonyms:C₁₈H₂₁N₅O₄S

Chemical Property of C₁₈H₂₁N₅O₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₁N₅O₄S

There total 6 articles about C₁₈H₂₁N₅O₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C18H19ClN4O4S (1539303-94-0) → C18H21N5O4S (1539303-95-1)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield:

4,6-dihydroxy-2-methylmercaptopyrimidine (1979-98-2) → C18H21N5O4S (1539303-95-1)

Guidance literature:

Multi-step reaction with 6 steps

1.1: trifluoroacetic acid / 0.5 h / 20 °C

1.2: 5 - 20 °C

2.1: trichlorophosphate; N,N-dimethyl-aniline / 2 h / 0 - 100 °C

3.1: triethylamine; ammonia / tetrahydrofuran; isopropyl alcohol / 5 h / 20 °C

4.1: triethylamine / tetrahydrofuran / 6 h / 20 °C

5.1: potassium carbonate; sodium iodide / acetone / 48 h / 20 °C

6.1: ammonium hydroxide / tetrahydrofuran / 2 h / 20 °C

With ammonium hydroxide; ammonia; potassium carbonate; N,N-dimethyl-aniline; triethylamine; trifluoroacetic acid; sodium iodide; trichlorophosphate; In tetrahydrofuran; isopropyl alcohol; acetone;

Reference yield:

2-(methylthio)-5-nitropyrimidine-4,6-diol (1979-97-1) → C18H21N5O4S (1539303-95-1)

Guidance literature:

Multi-step reaction with 5 steps

1: trichlorophosphate; N,N-dimethyl-aniline / 2 h / 0 - 100 °C

2: triethylamine; ammonia / tetrahydrofuran; isopropyl alcohol / 5 h / 20 °C

3: triethylamine / tetrahydrofuran / 6 h / 20 °C

4: potassium carbonate; sodium iodide / acetone / 48 h / 20 °C

5: ammonium hydroxide / tetrahydrofuran / 2 h / 20 °C

With ammonium hydroxide; ammonia; potassium carbonate; N,N-dimethyl-aniline; triethylamine; sodium iodide; trichlorophosphate; In tetrahydrofuran; isopropyl alcohol; acetone;

upstream raw materials:

4,6-dihydroxy-2-methylmercaptopyrimidine

2-(methylthio)-5-nitropyrimidine-4,6-diol

6-chloro-2-(methylsulfanyl)-5-nitropyrimidin-4-amine

ethyl (6-chloro-2-(methylthio)-5-nitropyrimidin-4-yl)carbamate

Downstream raw materials:

C₁₈H₂₁N₅O₆S

C₂₉H₄₄N₆O₅Si

C₂₂H₂₇N₅O₅

C₂₁H₂₅N₅O₅