1-trifluoromethyl-cyclobutanecarboxylic acid methyl-[4-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane-6-carbonyl)-benzyl]-amide

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Chemical Name:1-trifluoromethyl-cyclobutanecarboxylic acid methyl-[4-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane-6-carbonyl)-benzyl]-amide
CAS No.:936018-09-6
Molecular Formula:C₂₅H₃₃F₃N₂O₂
Molecular Weight:450.544
Hs Code.:

Synonyms:1-trifluoromethyl-cyclobutanecarboxylic acid methyl-[4-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane-6-carbonyl)-benzyl]-amide

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Chemical Property of 1-trifluoromethyl-cyclobutanecarboxylic acid methyl-[4-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane-6-carbonyl)-benzyl]-amide

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Technology Process of 1-trifluoromethyl-cyclobutanecarboxylic acid methyl-[4-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane-6-carbonyl)-benzyl]-amide

There total 1 articles about 1-trifluoromethyl-cyclobutanecarboxylic acid methyl-[4-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane-6-carbonyl)-benzyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 936019-95-3
(4-methylaminomethyl-phenyl)-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]oct-6-yl)-methanone

: 277756-45-3
(1-trifluoromethyl)cyclobutanecarboxylic acid

: 936018-09-6
1-trifluoromethyl-cyclobutanecarboxylic acid methyl-[4-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octane-6-carbonyl)-benzyl]-amide

Guidance literature:: (1-trifluoromethyl)cyclobutanecarboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; at 20 ℃; for 0.5h;

(4-methylaminomethyl-phenyl)-(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]oct-6-yl)-methanone; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 16h;