methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside

Base Information

• Chemical Name: methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside
• CAS No.: 192636-83-2
• Molecular Formula: C₂₁H₂₄O₆
• Molecular Weight: 373.41
• Mol file: 192636-83-2.mol

Synonyms:methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside

Chemical Property of methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

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Technology Process of methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside

There total 3 articles about methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

methyl 2-O-benzyl-4,6-O-benzylidene-3-O-triflyl-α-D-(3-2H)glucopyranoside (192636-92-3) → (4aR,6S,7R)-7-Benzyloxy-6-methoxy-2-phenyl-4,4a,6,7-tetrahydro-pyrano[3,2-d][1,3]dioxine + (4aR,6S,8aS)-7-Benzyloxy-6-methoxy-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxine + methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside (192636-83-2)

Guidance literature:

With n-butyllithium; In diethyl ether; hexane; for 1h; Ambient temperature;

DOI:10.1016/S0008-6215(97)00080-3

Reference yield: 35.0%

methyl 2-O-benzyl-4,6-O-benzylidene-3-O-triflyl-α-D-(3-2H)glucopyranoside (192636-92-3) → (4aR,6S,7R)-7-Benzyloxy-6-methoxy-2-phenyl-4,4a,6,7-tetrahydro-pyrano[3,2-d][1,3]dioxine + methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside (192636-83-2)

Guidance literature:

With potassium tert-butylate; In diethyl ether; Ambient temperature;

DOI:10.1016/S0008-6215(97)00168-7

Reference yield: 14.0%

benzyl bromide (100-39-0) + methyl 4,6-O-benzylidene-D-(3-2H)glucopyranoside → methyl 2-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside (192636-83-2) + methyl 2-O-benzyl-4,6-O-benzylidene-β-D-(3-2H)glucopyranoside (192636-86-5) + methyl 3-O-benzyl-4,6-O-benzylidene-β-D-(3-2H)glucopyranoside + methyl 3-O-benzyl-4,6-O-benzylidene-α-D-(3-2H)glucopyranoside

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; for 48h; Heating;

DOI:10.1016/S0008-6215(97)00080-3

upstream raw materials:

methyl 2-O-benzyl-4,6-O-benzylidene-3-O-triflyl-α-D-(3-2H)glucopyranoside

benzyl bromide

Downstream raw materials:

methyl 2-O-benzyl-4,6-O-benzylidene-3-O-triflyl-α-D-(3-2H)glucopyranoside