(Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)-N-hydroxyacetamide

Base Information

• Chemical Name: (Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)-N-hydroxyacetamide
• CAS No.: 1257346-68-1
• Molecular Formula: C₂₀H₁₈FNO₂S
• Molecular Weight: 355.433
• Mol file: 1257346-68-1.mol

Synonyms:(Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)-N-hydroxyacetamide

Chemical Property of (Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)-N-hydroxyacetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of (Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)-N-hydroxyacetamide

There total 1 articles about (Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)-N-hydroxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)acetic acid O-(tert-butyldimethylsilyl)hydroxyamide (1257346-71-6) → (Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)-N-hydroxyacetamide (1257346-68-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.ejmech.2010.08.019

upstream raw materials:

(Z)-2-(6-fluoro-2-methyl-3-(4-(methylthio)benzylidene)-3H-inden-1-yl)acetic acid O-(tert-butyldimethylsilyl)hydroxyamide