[(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol

Base Information

Chemical Name:[(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol
CAS No.:946065-81-2
Molecular Formula:C₂₄H₂₄N₂O₂
Molecular Weight:372.467
Hs Code.:

Synonyms:[(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol

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Chemical Property of [(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol

Chemical Property:

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Technology Process of [(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol

There total 5 articles about [(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 871918-46-6
benzyl (R)-1-((S)-4-(hydroxydiphenylmethyl)-4,5-dihydrooxazol-2-yl)-2-phenylethylcarbamate

: 946065-81-2
[(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1021/ol052300x

Reference yield:

: 871918-52-4
[(R)-1-((S)-2-Hydroxy-1-hydroxymethyl-2,2-diphenyl-ethylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester

: 946065-81-2
[(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol

Guidance literature:: Multi-step reaction with 3 steps

1: DMAP; triethylamine / 1,2-dichloro-ethane / 20 °C

2: 1.453 g / 1,2-dichloro-ethane / Heating

3: H₂ / Pd/C / methanol

With dmap; hydrogen; triethylamine; palladium on activated charcoal; In methanol; 1,2-dichloro-ethane;
DOI:10.1021/ol052300x

Reference yield:

: Toluene-4-sulfonic acid (S)-2-((R)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-3-hydroxy-3,3-diphenyl-propyl ester

: 946065-81-2
[(S)-2-((R)-1-Amino-2-phenyl-ethyl)-4,5-dihydro-oxazol-4-yl]-diphenyl-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.453 g / 1,2-dichloro-ethane / Heating

2: H₂ / Pd/C / methanol

With hydrogen; palladium on activated charcoal; In methanol; 1,2-dichloro-ethane;
DOI:10.1021/ol052300x