(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

Base Information

Chemical Name:(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester
CAS No.:666831-62-5
Molecular Formula:C₃₅H₄₈O₁₀Si
Molecular Weight:656.846
Hs Code.:

(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

Synonyms:(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

Suppliers and Price of (1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

There total 3 articles about (1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 108-24-7
acetic anhydride

: 666831-61-4
(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-6-(dimethyl-phenyl-silanyl)-8a-hydroxymethyl-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

: 666831-62-5
(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

Guidance literature:: With pyridine; dmap; at 20 ℃; for 16h;
DOI:10.1021/jo0355606

Reference yield:

: 666831-60-3
(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-6-(dimethyl-phenyl-silanyl)-8a-formyl-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

: 666831-62-5
(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / lithium tris[(3-ethyl-3-pentyl)oxy]aluminohydride / tetrahydrofuran / 22 h / -45 °C

2: 94 percent / pyridine; DMAP / 16 h / 20 °C

With pyridine; dmap; Lithium tris[(3-ethyl-3-pentyl)-oxy]aluminohydride; In tetrahydrofuran;
DOI:10.1021/jo0355606

Reference yield:

: 666831-59-0
(4S,4aS,7R,8aS)-4-{(R)-1-Acetoxy-2-[(1S,2S)-1-methoxycarbonyl-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentyl]-ethyl}-7-(dimethyl-phenyl-silanyl)-4a-formyl-2,5-dioxo-decahydro-naphthalene-1-carboxylic acid allyl ester

: 666831-62-5
(1S,2S)-1-{(R)-2-Acetoxy-2-[(1S,4aR,6R,8aS)-8a-acetoxymethyl-6-(dimethyl-phenyl-silanyl)-3,8-dioxo-decahydro-naphthalen-1-yl]-ethyl}-2-((R)-1-methoxy-ethyl)-5-oxo-cyclopentanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / morpholine; Pd(PPh₃)4 / tetrahydrofuran / 0.5 h / 20 °C

2: 72 percent / lithium tris[(3-ethyl-3-pentyl)oxy]aluminohydride / tetrahydrofuran / 22 h / -45 °C

3: 94 percent / pyridine; DMAP / 16 h / 20 °C

With morpholine; pyridine; dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; Lithium tris[(3-ethyl-3-pentyl)-oxy]aluminohydride; In tetrahydrofuran;
DOI:10.1021/jo0355606