4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

Base Information

Chemical Name:4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde
CAS No.:737800-15-6
Molecular Formula:C₃₅H₃₂Cl₂O₆
Molecular Weight:619.541
Hs Code.:

Synonyms:4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

Suppliers and Price of 4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

There total 7 articles about 4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 74-88-4
methyl iodide

: 737800-14-5
4,6-bis-benzyloxy-2-(3,5-dichloro-2,6-dihydroxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

: 737800-15-6
4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

Guidance literature:: With potassium carbonate; In acetone; at 40 ℃;
DOI:10.1016/j.tetlet.2004.05.063

Reference yield:

: 870-63-3
prenyl bromide

: 737800-15-6
4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

Guidance literature:: Multi-step reaction with 10 steps

1.1: n-BuLi / -78 °C

1.2: 78 percent / 1,2-dimethoxy-ethane / 0 °C

2.1: n-BuLi / -78 °C

2.2: 62 percent / 1,2-dimethoxy-ethane / 0 °C

3.1: 86 percent / LiAlH₄ / tetrahydrofuran

4.1: 99 percent / imidazole / dimethylformamide

5.1: MeI / 40 °C

5.2: NaBH₄ / methanol; tetrahydrofuran

5.3: 69 percent / aq. AcOH / tetrahydrofuran

6.1: 99 percent / n-BuLi / tetrahydrofuran / -78 - 0 °C

7.1: 100 percent / TBAF / tetrahydrofuran

8.1: 53 percent / IBX; DMSO / toluene

9.1: 100 percent / aq. HCl / tetrahydrofuran

10.1: 100 percent / K₂CO₃ / acetone / 40 °C

With 1H-imidazole; hydrogenchloride; lithium aluminium tetrahydride; n-butyllithium; tetrabutyl ammonium fluoride; potassium carbonate; dimethyl sulfoxide; methyl iodide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1016/j.tetlet.2004.05.063

Reference yield:

: 737800-16-7
[4,6-bis-benzyloxy-2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-3-(3-methyl-but-2-enyl)-phenyl]-methanol

: 737800-15-6
4,6-bis-benzyloxy-2-(3,5-dichloro-2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-(3-methyl-but-2-enyl)-benzaldehyde

Guidance literature:: Multi-step reaction with 7 steps

1.1: 99 percent / imidazole / dimethylformamide

2.1: MeI / 40 °C

2.2: NaBH₄ / methanol; tetrahydrofuran

2.3: 69 percent / aq. AcOH / tetrahydrofuran

3.1: 99 percent / n-BuLi / tetrahydrofuran / -78 - 0 °C

4.1: 100 percent / TBAF / tetrahydrofuran

5.1: 53 percent / IBX; DMSO / toluene

6.1: 100 percent / aq. HCl / tetrahydrofuran

7.1: 100 percent / K₂CO₃ / acetone / 40 °C

With 1H-imidazole; hydrogenchloride; n-butyllithium; tetrabutyl ammonium fluoride; potassium carbonate; dimethyl sulfoxide; methyl iodide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1016/j.tetlet.2004.05.063