[4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate

Base Information

• Chemical Name: [4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate
• CAS No.: 888972-62-1
• Molecular Formula: C₂HF₃O₂*C₁₉H₂₉ClN₂O₃
• Molecular Weight: 482.928
• Mol file: 888972-62-1.mol

Synonyms:[4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate

Chemical Property of [4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate

There total 1 articles about [4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S)-4-[[5-chloro-2-[2-(1,1-dimethylethoxy)-2-oxoethoxy]phenyl]methyl]-2-ethyl-1-piperazinecarboxylic acid, 1,1-dimethylethyl ester (888972-60-9) + trifluoroacetic acid (76-05-1) → [4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate (888972-62-1)

Guidance literature:

In dichloromethane; at 20 ℃; for 24h;

Reference yield:

[4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate (888972-62-1) + benzenesulfonyl chloride (98-09-9) → [4-chloro-2-[[(3S)-3-ethyl-4-(phenylsulfonyl)-1-piperazinyl]methyl]phenoxy]-acetic acid

Guidance literature:

[4-chloro-2-[[(3S)-3-ethyl-1-piperazinyl]methyl]phenoxy]-acetic acid, 1,1-dimethylethyl ester trifluoroacetate; benzenesulfonyl chloride; With sodium hydrogencarbonate; In dichloromethane; water; for 16h;

With trifluoroacetic acid; In dichloromethane; for 16h;

upstream raw materials:

(2S)-4-[[5-chloro-2-[2-(1,1-dimethylethoxy)-2-oxoethoxy]phenyl]methyl]-2-ethyl-1-piperazinecarboxylic acid, 1,1-dimethylethyl ester

trifluoroacetic acid