10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene

Base Information

Chemical Name:10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene
CAS No.:206058-81-3
Molecular Formula:C₂₅H₂₈O₆
Molecular Weight:424.494
Hs Code.:

10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1<i>H</i>-benzo[<i>g</i>]isochromene

Synonyms:10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene

Suppliers and Price of 10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene

There total 7 articles about 10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 228701-37-9
10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-1-ol

: 206058-81-3
10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at 0 ℃; for 1h;
DOI:10.7164/antibiotics.51.383

Reference yield:

: 6110-37-8
methyl 2,4-dimethoxy-6-methylbenzoate

: 206058-81-3
10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / LDA / tetrahydrofuran / 4.5 h / -78 - 0 °C

2: 89 percent / cyclohexene / 10 percent Pd-C / toluene / 12 h / 20 °C

3: 97 percent / K₂CO₃ / acetone / 7 h / 55 °C

4: DIBAL / toluene / 2 h / -78 °C

5: 70 percent / Et₃SiH; TFA / CH₂Cl₂ / 1 h / 0 °C

With triethylsilane; diisobutylaluminium hydride; potassium carbonate; trifluoroacetic acid; lithium diisopropyl amide; cyclohexene; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; acetone; toluene; 1: Cycloaddition / 2: Aromatisation / 3: Etherification / 4: Reduction / 5: deoxygenation;
DOI:10.7164/antibiotics.51.383

Reference yield:

: 54826-92-5
(5R,6S)-5,6-dihydro-5-hydroxy-6-methylpyran-2-one

: 206058-81-3
10-benzyloxy-7,9-dimethoxy-4-methoxymethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / P₂O₅ / CH₂Cl₂ / 0.25 h / 20 °C

2: 85 percent / LDA / tetrahydrofuran / 4.5 h / -78 - 0 °C

3: 89 percent / cyclohexene / 10 percent Pd-C / toluene / 12 h / 20 °C

4: 97 percent / K₂CO₃ / acetone / 7 h / 55 °C

5: DIBAL / toluene / 2 h / -78 °C

6: 70 percent / Et₃SiH; TFA / CH₂Cl₂ / 1 h / 0 °C

With triethylsilane; phosphorus pentoxide; diisobutylaluminium hydride; potassium carbonate; trifluoroacetic acid; lithium diisopropyl amide; cyclohexene; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; acetone; toluene; 1: Substitution / 2: Cycloaddition / 3: Aromatisation / 4: Etherification / 5: Reduction / 6: deoxygenation;
DOI:10.7164/antibiotics.51.383