(baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

Base Information

Chemical Name:(baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate
CAS No.:534572-31-1
Molecular Formula:C₄₃H₄₇NO₁₃
Molecular Weight:785.845
Hs Code.:

Synonyms:(baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

Suppliers and Price of (baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

There total 3 articles about (baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 534572-16-2
(7-TES-baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

: 534572-31-1
(baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

Guidance literature:: With pyridine; hydrogen fluoride; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/ejoc.200500243

Reference yield:

: 115437-21-3
7-(triethylsilyl)baccatin III

: 534572-31-1
(baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 36 percent / DCC; 4-PP / toluene / 24 h / 20 °C

2: 97 percent / pyridine; HF / tetrahydrofuran / 20 °C

With pyridine; hydrogen fluoride; dicyclohexyl-carbodiimide; In tetrahydrofuran; toluene;
DOI:10.1002/ejoc.200500243

Reference yield:

: 534572-15-1
(+/-)-2-phenylspiro(cyclopropane-1',4-oxazoline)-5-carboxylic acid

: 534572-31-1
(baccatin III)-13-yl (5S)-2-phenylspiro[cyclopropane-1',4-oxazoline]-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 36 percent / DCC; 4-PP / toluene / 24 h / 20 °C

2: 97 percent / pyridine; HF / tetrahydrofuran / 20 °C

With pyridine; hydrogen fluoride; dicyclohexyl-carbodiimide; In tetrahydrofuran; toluene;
DOI:10.1002/ejoc.200500243