1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane

Base Information

• Chemical Name: 1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane
• CAS No.: 1233964-12-9
• Molecular Formula: C₂₆H₂₁F₃N₂O
• Molecular Weight: 434.461
• Mol file: 1233964-12-9.mol

Synonyms:1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane

Chemical Property of 1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane

There total 2 articles about 1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,2,2-trifluoro-1-(4-phenoxyphenyl)-ethanone (70783-32-3) + aniline (62-53-3) → 1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane (1233964-12-9)

Guidance literature:

2,2,2-trifluoro-1-(4-phenoxyphenyl)-ethanone; aniline; With aniline hydrochloride; at 185 ℃; for 24h;

With sodium hydrogencarbonate; In water; at 20 ℃;

DOI:10.1016/j.polymer.2010.06.005

Reference yield:

4-Bromodiphenyl ether (101-55-3) → 1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane (1233964-12-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium hydroxide / 4 h / 5 °C

1.2: 20 - 65 °C

1.3: 20 °C

2.1: aniline hydrochloride / 24 h / 185 °C

2.2: 20 °C

With aniline hydrochloride; lithium hydroxide; 1.2: Grignard reaction;

DOI:10.1016/j.polymer.2010.06.005

Reference yield:

1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane (1233964-12-9) → 5-[1,1-bis(4-aminophenyl)-2,2,2-trifluoroethyl]-2-(4-sulfophenoxy)benzenesulfonic acid disodium salt

Guidance literature:

1,1-bis(4-aminophenyl)-1-(4-phenoxyphenyl)-2,2,2-trifluoroethane; With sulfuric acid; sulfur trioxide; at 0 - 40 ℃; for 6.5h;

With sodium hydroxide; In water; Cooling with ice;

DOI:10.1016/j.polymer.2010.06.005

upstream raw materials:

4-Bromodiphenyl ether

2,2,2-trifluoro-1-(4-phenoxyphenyl)-ethanone

aniline

Downstream raw materials:

5-[1,1-bis(4-aminophenyl)-2,2,2-trifluoroethyl]-2-(4-sulfophenoxy)benzenesulfonic acid