5-ACETYLAMINO-3-NITRO 1,2-XYLIN

Base Information

• Chemical Name: 5-ACETYLAMINO-3-NITRO 1,2-XYLIN
• CAS No.: 857571-00-7
• Molecular Formula: C10H12 N2 O3
• Molecular Weight: 208.217
• Mol file: 857571-00-7.mol

Synonyms:3',4'-Acetoxylidide,5'-nitro- (5CI); 4,5-Dimethyl-3-nitroacetanilide

Chemical Property of 5-ACETYLAMINO-3-NITRO 1,2-XYLIN

Chemical Property:

• Boiling Point: 380.1±30.0 °C(Predicted)
• PKA: 14.21±0.70(Predicted)
• PSA: 74.92000
• Density: 1.247±0.06 g/cm3(Predicted)
• LogP: 2.76620
• Storage Temp.: 2-8°C

Purity/Quality:

95% ^*data from raw suppliers

N-(3,4-Dimethyl-5-nitrophenyl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-ACETYLAMINO-3-NITRO 1,2-XYLIN

There total 2 articles about 5-ACETYLAMINO-3-NITRO 1,2-XYLIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-o-xylene (95-64-7) → acetic acid-(3,4-dimethyl-5-nitro-anilide) (857571-00-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous acetic acid

2: water; sulfuric acid; nitric acid

With sulfuric acid; water; nitric acid; acetic acid;

DOI:10.1039/jr9470000910

Reference yield:

N-(3,4-dimethylphenyl)acetamide (2198-54-1) → acetic acid-(3,4-dimethyl-5-nitro-anilide) (857571-00-7)

Guidance literature:

With sulfuric acid; water; nitric acid;

DOI:10.1039/jr9470000910

Reference yield:

1-bromo-4-methoxy-benzene (104-92-7) + acetic acid-(3,4-dimethyl-5-nitro-anilide) (857571-00-7) → (3,4-dimethyl-5-nitro-phenyl)-(4-methoxy-phenyl)-amine (857974-87-9)

Guidance literature:

With copper; potassium carbonate; potassium iodide; at 240 ℃; beim Erwaermen der in Benzin loeslichen Anteile des Reaktionsprodukts mit wss.Salzsaeure;

DOI:10.1039/jr9470000910

upstream raw materials:

N-(3,4-dimethylphenyl)acetamide

4-amino-o-xylene

Downstream raw materials:

(3,4-dimethyl-5-nitro-phenyl)-(4-methoxy-phenyl)-amine

N-(4-chloro-phenyl)-N-(3,4-dimethyl-5-nitro-phenyl)-acetamide

3,4-dimethyl-5-nitro-aniline

N¹-(4-methoxy-phenyl)-4,5-dimethyl-m-phenylenediamine