N-(4-(tert-butyl)phenyl)-4-pentenamide

Base Information

• Chemical Name: N-(4-(tert-butyl)phenyl)-4-pentenamide
• CAS No.: 1266062-79-6
• Molecular Formula: C₁₅H₂₁NO
• Molecular Weight: 231.338
• Mol file: 1266062-79-6.mol

Synonyms:N-(4-(tert-butyl)phenyl)-4-pentenamide

Chemical Property of N-(4-(tert-butyl)phenyl)-4-pentenamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-(tert-butyl)phenyl)-4-pentenamide

There total 1 articles about N-(4-(tert-butyl)phenyl)-4-pentenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pent-4-enoic acid (591-80-0) + 4-tert-Butylaniline (769-92-6) → N-(4-(tert-butyl)phenyl)-4-pentenamide (1266062-79-6)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃;

DOI:10.1021/ja400124t

Reference yield: 85.0%

N-(4-(tert-butyl)phenyl)-4-pentenamide (1266062-79-6) → 1-(4-(tert-butyl)phenyl)-5-(fluoromethyl)pyrrolidin-2-one (1427449-76-0)

Guidance literature:

With silver nitrate; Selectfluor; In dichloromethane; water; at 20 ℃; for 36h; Reagent/catalyst; Solvent; Schlenk technique; Inert atmosphere;

DOI:10.1021/ja400124t

Reference yield: 81.0%

N-(4-(tert-butyl)phenyl)-4-pentenamide (1266062-79-6) + 1-(3-(3,3,3-trifluoroprop-1-en-2-yl)phenyl)ethan-1-one → 5-(3-(3-acetylphenyl)-4,4-difluorobut-3-en-1-yl)-1-(4-(tert-butyl)phenyl)pyrrolidin-2-one

Guidance literature:

With [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; tetra-n-butylammonium dimethyl phosphate; In acetonitrile; at 27 ℃; for 12h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/acs.orglett.1c03329

upstream raw materials:

pent-4-enoic acid

4-tert-Butylaniline

Downstream raw materials:

1-(4-(tert-butyl)phenyl)-5-(fluoromethyl)pyrrolidin-2-one