1-aminopiperidin-2-one hydrochloride

Base Information

• Chemical Name: 1-aminopiperidin-2-one hydrochloride
• CAS No.: 31967-08-5
• Molecular Formula: C₅H₁₀N₂O*ClH
• Molecular Weight: 150.608
• Mol file: 31967-08-5.mol

Synonyms:1-aminopiperidin-2-one hydrochloride

Chemical Property of 1-aminopiperidin-2-one hydrochloride

Chemical Property:

• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99% ^*data from raw suppliers

1-Aminopiperidin-2-onehydrochloride >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-aminopiperidin-2-one hydrochloride

There total 1 articles about 1-aminopiperidin-2-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl (3S)-2-oxopiperidinylcarbamate (1123192-34-6) → 1-aminopiperidin-2-one hydrochloride (31967-08-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h;

Reference yield:

(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]acrylic acid (870839-41-1) + 1-aminopiperidin-2-one hydrochloride (31967-08-5) → (E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-N-(2-oxopiperidin-1-yl)acrylamide (1123192-36-8)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;

upstream raw materials:

tert-butyl (3S)-2-oxopiperidinylcarbamate

Downstream raw materials:

(E)-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-N-(2-oxopiperidin-1-yl)acrylamide

Refernces

• 1、 -. "IMIDAZOYL PYRIDINE COMPOUNDS AND SALTS THEREOF". Page/Page column 97. . Retrieved 2009/04/24.