2-acetamidophenyl 1-naphthylmethyl ketone

Base Information

Chemical Name:2-acetamidophenyl 1-naphthylmethyl ketone
CAS No.:80749-36-6
Molecular Formula:C₂₀H₁₇NO₂
Molecular Weight:303.36
Hs Code.:

Synonyms:2-acetamidophenyl 1-naphthylmethyl ketone

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Chemical Property of 2-acetamidophenyl 1-naphthylmethyl ketone

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Technology Process of 2-acetamidophenyl 1-naphthylmethyl ketone

There total 4 articles about 2-acetamidophenyl 1-naphthylmethyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 80749-34-4
2-methyl-3-(1-naphthylmethyl)indole

: 80749-36-6
2-acetamidophenyl 1-naphthylmethyl ketone

Guidance literature:: With oxygen; ozone; In ethyl acetate; for 11h;

Reference yield:

: 95-20-5
2-methyl-1H-indole

: 80749-36-6
2-acetamidophenyl 1-naphthylmethyl ketone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) EtMgBr / 1.) Et₂O, 2 h, reflux; 2.) Et₂O, 30 min

2: 1.) BH₃*SMe₂, 2.) CH₃OH / 1.) THF, 0 deg C, 2 h; r.t., 2 h, 2.) THF, 1 h, reflux

3: 71 percent / O₃/O₂ / ethyl acetate / 11 h

With methanol; dimethylsulfide borane complex; ethylmagnesium bromide; oxygen; ozone; In ethyl acetate;

Reference yield:

: 3506-84-1
4-(1-naphthyl)-2-butanone

: 80749-36-6
2-acetamidophenyl 1-naphthylmethyl ketone

Guidance literature:: Multi-step reaction with 2 steps

1: Erhitzen des Reaktionsprodukts mit Essigsaeure und dem Borfluorid-Aether-Addukt

2: Ozonolyse

DOI:10.1039/jr9530003440