3-chloro-6-hydrazinylPyridazine hydrochloride

Base Information

• Chemical Name: 3-chloro-6-hydrazinylPyridazine hydrochloride
• CAS No.: 856847-88-6
• Molecular Formula: C4H5 Cl N4 . Cl H
• Molecular Weight: 181.024
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID60474501
• Mol file: 856847-88-6.mol

Synonyms:856847-88-6;3-chloro-6-hydrazinylPyridazine hydrochloride;(6-chloropyridazin-3-yl)hydrazine;hydrochloride;PYRIDAZINE, 3-CHLORO-6-HYDRAZINO-, HCL;AGN-PC-00HMCX;SCHEMBL25247217;DTXSID60474501;AKOS015917482;AS-41921;FT-0712350

Chemical Property of 3-chloro-6-hydrazinylPyridazine hydrochloride

Chemical Property:

• Vapor Pressure: 1.12E-06mmHg at 25°C
• Boiling Point: 402.2°C at 760 mmHg
• Flash Point: 197°C
• PSA: 63.83000
• LogP: 1.99090
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 179.9969516
• Heavy Atom Count: 10
• Complexity: 88.6

Purity/Quality:

98%Min ^*data from raw suppliers

3-Chloro-6-hydrazinylpyridazinehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NN=C1NN)Cl.Cl

Technology Process of 3-chloro-6-hydrazinylPyridazine hydrochloride

There total 1 articles about 3-chloro-6-hydrazinylPyridazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,6-dichlorpyridazine (141-30-0) → 3-chloro-6-hydrazinylpyridazine hydrochloride (856847-88-6)

Guidance literature:

With hydrazine hydrate; In ethanethiol; at 100 ℃; for 2h; Microwave irradiation;

DOI:10.1021/acs.jmedchem.1c01136

Reference yield: 84.0%

3-chloro-6-hydrazinylpyridazine hydrochloride (856847-88-6) + 6-(4-chlorophenyl)-4,6-dioxohexanoic acid (111881-78-8) → 3-(5-(4-chlorophenyl)-1-(3-chloropyridazin-6-yl)-3-pyrazolyl]propionic acid (153708-81-7)

Guidance literature:

With triethylamine; In methanol; at 20 ℃; Inert atmosphere; Reflux;

Reference yield: 84.0%

3-chloro-6-hydrazinylpyridazine hydrochloride (856847-88-6) + 4,6-dioxo-6-(4-fluorophenyl)hexanoic acid → 3-(1-(6-chloropyridazin-3-yl)-5-(4-fluorophenyl)-1H-pyrazol-3-yl)propanoic acid (1254703-63-3)

Guidance literature:

With triethylamine; In methanol; at 20 ℃; Inert atmosphere; Reflux;

upstream raw materials:

3,6-dichlorpyridazine

Downstream raw materials:

C₁₆H₁₂BrClN₄O₂

C₁₇H₁₂ClF₃N₄O₂

C₁₇H₁₅ClN₄O₄S

C₁₆H₁₃ClN₄O₂