ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate

Base Information

Chemical Name:ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate
CAS No.:1620558-16-8
Molecular Formula:C₂₄H₂₄F₃N₃O₃
Molecular Weight:459.468
Hs Code.:

Synonyms:ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate

Suppliers and Price of ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate

There total 6 articles about ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 1376395-94-6
C₁₆H₂₃N₃O₃

: 1620558-16-8
ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate

Guidance literature:: With sodium meta bi sulfate; In water; at 20 ℃; for 2h; Green chemistry;
DOI:10.1016/j.ejmech.2014.06.060

Reference yield: 90.0%

: 152782-75-7
sodium hydroxy(4-(trifluoromethyl)phenyl)methanesulfonate

: 1376395-94-6
C₁₆H₂₃N₃O₃

: 1620558-16-8
ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate

Guidance literature:: In N,N-dimethyl-formamide; at 90 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2013.06.025

Reference yield:

: 367-80-6
ethyl 4-fluoro-3-nitrobenzoate

: 1620558-16-8
ethyl 2-(4-(trifluoromethyl)phenyl)-1-(3-(2-oxopyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole-5-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 1 h / 20 °C

2: ammonium formate; palladium 10% on activated carbon / ethanol / 20 °C

3: sodium meta bi sulfate / water / 2 h / 20 °C / Green chemistry

With sodium meta bi sulfate; palladium 10% on activated carbon; ammonium formate; In ethanol; water;
DOI:10.1016/j.ejmech.2014.06.060