[2,2'-Bifuran]-5-carboxylic acid

Base Information

• Chemical Name: [2,2'-Bifuran]-5-carboxylic acid
• CAS No.: 856122-70-8
• Molecular Formula: C₉H₆O₄
• Molecular Weight: 178.144
• Hs Code.: 2932190090
• DSSTox Substance ID: DTXSID20596379
• Wikidata: Q82491617
• Mol file: 856122-70-8.mol

Synonyms:[2,2'-Bifuran]-5-carboxylic acid;856122-70-8;5-(furan-2-yl)furan-2-carboxylic acid;[2,2'-Bifuran]-5-carboxylicacid;2,2'-bifuran-5-carboxylic acid;DTXSID20596379;AKOS002666071;[2,2-BIFURAN]-5-CARBOXYLICACID;DB-328254;CS-0456276;EN300-109059;5-(FURAN-2-YL)-FURAN-2-CARBOXYLIC ACID;F2167-0889;Z1179935372

Chemical Property of [2,2'-Bifuran]-5-carboxylic acid

Chemical Property:

• PSA: 63.58000
• LogP: 2.23780
• Storage Temp.: 2-8°C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 178.02660867
• Heavy Atom Count: 13
• Complexity: 204

Purity/Quality:

97% ^*data from raw suppliers

5-(furan-2-yl)furan-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)C2=CC=C(O2)C(=O)O

Technology Process of [2,2'-Bifuran]-5-carboxylic acid

There total 4 articles about [2,2'-Bifuran]-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2'-bifuran (5905-00-0) → [2,2']bifuryl-5-carboxylic acid (856122-70-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen cyanide; diethyl ether; hydrogen chloride / anschliessendes Behandeln mit Wasser

2: silver oxide; aq.-ethanolic KOH-solution

With hydrogenchloride; potassium hydroxide; diethyl ether; hydrogen cyanide; silver(l) oxide;

DOI:10.1002/hlca.193201501116

Reference yield:

ethyl 3-(2-furyl)-3-oxopropanoate (615-09-8) → [2,2']bifuryl-5-carboxylic acid (856122-70-8)

Guidance literature:

Multi-step reaction with 4 steps

1: aq. NaOH solution / Erwaermen der bei 86-98/0.5 Torr siedenden Anteile des Reaktionsprodukts mit wss.-aethanol. Kalilauge

2: quinoline; copper oxide-chromium oxide / 200 °C

3: hydrogen cyanide; diethyl ether; hydrogen chloride / anschliessendes Behandeln mit Wasser

4: silver oxide; aq.-ethanolic KOH-solution

With quinoline; hydrogenchloride; potassium hydroxide; sodium hydroxide; diethyl ether; hydrogen cyanide; copper oxide-chromium oxide; silver(l) oxide;

DOI:10.1002/hlca.193201501116

Reference yield:

[2,2']bifuranyl-5-carbaldehyde (16303-60-9) → [2,2']bifuryl-5-carboxylic acid (856122-70-8)

Guidance literature:

With potassium hydroxide; silver(l) oxide;

DOI:10.1002/hlca.193201501116

upstream raw materials:

[2,2']bifuranyl-5-carbaldehyde

2,2'-bifuran

ethyl 3-(2-furyl)-3-oxopropanoate

[2,2']bifuranyl-3-carboxylic acid