(3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester

Base Information

Chemical Name:(3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester
CAS No.:73608-93-2
Molecular Formula:C₂₇H₃₅NO₅
Molecular Weight:453.579
Hs Code.:

Synonyms:(3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester

Suppliers and Price of (3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester

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Technology Process of (3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester

There total 3 articles about (3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 69700-17-0
1-(3-(benzyloxy)-4-methoxyphenyl)-2-bromoethan-1-one

: 56246-53-8
(+)-ethyl cincholoiponate

: 73608-93-2
(3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester

Guidance literature:: With potassium carbonate; In benzene; at 50 - 55 ℃; for 15h;
DOI:10.1248/cpb.33.583

Reference yield:

: 118-10-5
Cinchonin

: 73608-93-2
(3R,4S)-(+)-1-(3-benzyloxy-4-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

2: 71 percent / K₂CO₃ / benzene / 15 h / 50 - 55 °C

With potassium carbonate; In benzene;
DOI:10.1248/cpb.33.583