1,1-bis(phenylthio)-1-phenylpentane

Base Information

• Chemical Name: 1,1-bis(phenylthio)-1-phenylpentane
• CAS No.: 77815-76-0
• Molecular Formula: C₂₃H₂₄S₂
• Molecular Weight: 364.576
• Mol file: 77815-76-0.mol

Synonyms:1,1-bis(phenylthio)-1-phenylpentane

Chemical Property of 1,1-bis(phenylthio)-1-phenylpentane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-bis(phenylthio)-1-phenylpentane

There total 2 articles about 1,1-bis(phenylthio)-1-phenylpentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-iodo-butane (542-69-8) + bis(phenylthio)methylbenzene (7695-69-4) → 1,1-bis(phenylthio)-1-phenylpentane (77815-76-0)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; at -5 - 0 ℃; for 1h;

Reference yield: 64.0%

1-bromo-butane (109-65-9) + bis(phenylthio)methylbenzene (7695-69-4) → 1,1-bis(phenylthio)-1-phenylpentane (77815-76-0)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; at -5 - 0 ℃; for 1h;

Reference yield:

1,1-bis(phenylthio)-1-phenylpentane (77815-76-0) → phenyl butyl ketone (1009-14-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) lithium naphthalenide

2: 85percent m-chloroperbenzoic acid / CH₂Cl₂ / 1.5 h / -23 °C

3: 2.) 1 M mercury(II) acetate / 1.) THF, reflux, 4 h, 2.) THF, water, 17 h, room temperature

With mercury(II) diacetate; naphthalen-1-yl-lithium; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1039/P19860000195

upstream raw materials:

1-bromo-butane

bis(phenylthio)methylbenzene

1-iodo-butane

Downstream raw materials:

1-phenyl-1-phenylthio-1-trimethylsilylpentane

phenyl butyl ketone

Refernces

• 1、 Ager, David J.. "ALKYLATIONS OF BIS(PHENYLTHIO)ACETALS". . p. 4763 - 4766. Retrieved 2007/10/02.