C₁₃H₁₇ON

Base Information

• Chemical Name: C₁₃H₁₇ON
• CAS No.: 951240-71-4
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.284
• Mol file: 951240-71-4.mol

Synonyms:C₁₃H₁₇ON

Chemical Property of C₁₃H₁₇ON

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₃H₁₇ON

There total 9 articles about C₁₃H₁₇ON which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H25O3SN (951240-66-7) → C13H17ON (951240-71-4)

Guidance literature:

With trifluorormethanesulfonic acid; methoxybenzene; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/ol0713988

Reference yield:

C9H16NO3SBr (951240-63-4) → C13H17ON (951240-71-4)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 2.5 h / 0 - 20 °C

2: CuBr*SMe₂ / tetrahydrofuran; diethyl ether / -40 - -35 °C

3: sodium carbonate / Pd(Ph₃P)4 / ethanol; toluene; H₂O / 0.75 h / 80 °C

4: anisole; triflic acid / CH₂Cl₂ / 0.5 h / 0 °C

With dmap; copper(I) bromide dimethylsulfide complex; trifluorormethanesulfonic acid; sodium carbonate; methoxybenzene; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; toluene; 2: Grignard reaction / 3: Suzuki coupling;

DOI:10.1021/ol0713988

Reference yield:

C13H25NO6SBrP (951240-64-5) → C13H17ON (951240-71-4)

Guidance literature:

Multi-step reaction with 3 steps

1: CuBr*SMe₂ / tetrahydrofuran; diethyl ether / -40 - -35 °C

2: sodium carbonate / Pd(Ph₃P)4 / ethanol; toluene; H₂O / 0.75 h / 80 °C

3: anisole; triflic acid / CH₂Cl₂ / 0.5 h / 0 °C

With copper(I) bromide dimethylsulfide complex; trifluorormethanesulfonic acid; sodium carbonate; methoxybenzene; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; toluene; 1: Grignard reaction / 2: Suzuki coupling;

DOI:10.1021/ol0713988

upstream raw materials:

C₁₇H₂₅O₃SN

C₉H₁₆NO₃SBr

C₁₃H₂₅NO₆SBrP

C₁₀H₁₈NO₂SBr

Downstream raw materials:

C₁₄H₁₉ON

3-[(3R,4R)-3,4-dimethylpiperidin-4-yl]phenol

(3R,4R)-4-(3-methoxyphenyl)-3,4-dimethylpiperidine

(+)-1,3(R),4(R)-Trimethyl-4-(3-methoxyphenyl)piperidine

Refernces