1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea

Base Information

• Chemical Name: 1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea
• CAS No.: 153564-35-3
• Molecular Formula: C₁₇H₂₄Cl₂N₂O₃
• Molecular Weight: 375.295
• Mol file: 153564-35-3.mol

Synonyms:1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea

Chemical Property of 1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea

There total 3 articles about 1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

ethyl 6-<(3,4-dichlorophenyl)amino>hexanoate (153564-34-2) + N,N-Dimethylcarbamoyl chloride (79-44-7) → 1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea (153564-35-3)

Guidance literature:

With pyridine; In acetonitrile; for 5040h;

DOI:10.1021/jf00038a014

Reference yield:

6-bromo-hexanoic acid ethyl ester (25542-62-5) → 1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea (153564-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 33 percent / NaOAc*3H₂O / dimethylsulfoxide / 13 h / 80 °C

2: 94 percent / pyridine / acetonitrile / 5040 h

With pyridine; sodium acetate; In dimethyl sulfoxide; acetonitrile;

DOI:10.1021/jf00038a014

Reference yield:

m,p-dichloroaniline (95-76-1) → 1-(3,4-dichlorophenyl)-1-<5-(ethylcarboxy)pentyl>-3,3-dimethylurea (153564-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 33 percent / NaOAc*3H₂O / dimethylsulfoxide / 13 h / 80 °C

2: 94 percent / pyridine / acetonitrile / 5040 h

With pyridine; sodium acetate; In dimethyl sulfoxide; acetonitrile;

DOI:10.1021/jf00038a014

upstream raw materials:

ethyl 6-<(3,4-dichlorophenyl)amino>hexanoate

N,N-Dimethylcarbamoyl chloride

6-bromo-hexanoic acid ethyl ester

m,p-dichloroaniline