N-[4-chloro-2-(1-{4⁽³⁾-oxo-quinazolin-3-yl}imino)ethylphenyl]-trifluoromethanesulfonamide

Base Information

• Chemical Name: N-[4-chloro-2-(1-{4⁽³⁾-oxo-quinazolin-3-yl}imino)ethylphenyl]-trifluoromethanesulfonamide
• CAS No.: 951781-23-0
• Molecular Formula: C₁₇H₁₂ClF₃N₄O₃S
• Molecular Weight: 444.821

Synonyms:N-[4-chloro-2-(1-{4⁽³⁾-oxo-quinazolin-3-yl}imino)ethylphenyl]-trifluoromethanesulfonamide

Chemical Property of N-[4-chloro-2-(1-{4⁽³⁾-oxo-quinazolin-3-yl}imino)ethylphenyl]-trifluoromethanesulfonamide

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Technology Process of N-[4-chloro-2-(1-{4⁽³⁾-oxo-quinazolin-3-yl}imino)ethylphenyl]-trifluoromethanesulfonamide

There total 1 articles about N-[4-chloro-2-(1-{4⁽³⁾-oxo-quinazolin-3-yl}imino)ethylphenyl]-trifluoromethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

N-(2-acetyl-4-chlorophenyl)trifluoromethanesulfonamide (880473-75-6) + 3-amino-3,4-dihydroquinazolin-4-one (14663-46-8) → N-[4-chloro-2-(1-{4(3)-oxo-quinazolin-3-yl}imino)ethylphenyl]-trifluoromethanesulfonamide (951781-23-0)

Guidance literature:

toluene-4-sulfonic acid; In toluene; for 20h; Heating / reflux;

upstream raw materials:

N-(2-acetyl-4-chlorophenyl)trifluoromethanesulfonamide

3-amino-3,4-dihydroquinazolin-4-one

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