methyl phenylacetate

Base Information

• Chemical Name: methyl phenylacetate
• CAS No.: 87574-08-1
• Molecular Formula: C₂₁H₁₉NO₄S
• Molecular Weight: 381.452
• Mol file: 87574-08-1.mol

Synonyms:methyl phenylacetate

Chemical Property of methyl phenylacetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of methyl phenylacetate

There total 2 articles about methyl phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2-(1H-pyrrol-1-yl)benzoate (10333-67-2) → methyl phenylacetate (87574-08-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 53 percent / methanol / 48 h / 4 °C

2: 1) NaBH₄, 2) 85 percent KOH / 1) methanol, room temp., 45 min.; 2) reflux, 1.5 h

With potassium hydroxide; sodium tetrahydroborate; In methanol;

Reference yield:

bromo-phenyl-acetic acid methyl ester (37167-62-7,3042-81-7,61139-20-6) + 2-(2-Thiocyanato-pyrrol-1-yl)-benzoic acid methyl ester (87573-97-5) → methyl phenylacetate (87574-08-1)

Guidance literature:

With potassium hydroxide; sodium tetrahydroborate; Yield given. Multistep reaction; 1) methanol, room temp., 45 min.; 2) reflux, 1.5 h;

Reference yield: 20.0%

methyl phenylacetate (87574-08-1) → 5-phenyl-6-oxopyrrolo<1,2-a><3,1>benzothiazepine (87574-09-2)

Guidance literature:

With potassium tert-butylate; In toluene; at 100 - 110 ℃; for 4h;

upstream raw materials:

bromo-phenyl-acetic acid methyl ester

2-(2-Thiocyanato-pyrrol-1-yl)-benzoic acid methyl ester

methyl 2-(1H-pyrrol-1-yl)benzoate

Downstream raw materials:

5-phenyl-6-oxopyrrolo<1,2-a><3,1>benzothiazepine