5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine

Base Information

• Chemical Name: 5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine
• CAS No.: 123705-00-0
• Molecular Formula: C₂₁H₁₉N₅O₂
• Molecular Weight: 373.414

Synonyms:5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine

Chemical Property of 5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine

There total 3 articles about 5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

(2-chloroethyl)dimethylamine hydrochloride (4584-46-7) + 4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine (123705-04-4) → 5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine (123705-00-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 70 ℃; for 20h;

DOI:10.1002/jhet.5570260246

Reference yield:

α-ethoxyoxalyl-1-phenyl-5-(1-pyrryl)pyrazole-4-acetonitrile (123705-03-3) → 5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine (123705-00-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / polyphosphoric acid / 1 h / 90 °C

2: 44 percent / K₂CO₃ / dimethylformamide / 20 h / 70 °C

With PPA; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1002/jhet.5570260246

Reference yield:

2-[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]acetonitrile (112633-61-1) → 5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine (123705-00-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 61 percent / Na, EtOH / 20 h / Ambient temperature

2: 76 percent / polyphosphoric acid / 1 h / 90 °C

3: 44 percent / K₂CO₃ / dimethylformamide / 20 h / 70 °C

With PPA; ethanol; sodium; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1002/jhet.5570260246

upstream raw materials:

(2-chloroethyl)dimethylamine hydrochloride

4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine

α-ethoxyoxalyl-1-phenyl-5-(1-pyrryl)pyrazole-4-acetonitrile

2-[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]acetonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 123705-00-0 5-(2-dimethylaminoethyl)-4,6-dioxo-1-phenyl-1,4,5,6-tetrahydropyrazolo<3,4-e>pyrrolo<3,4-g>indolizine

Send

Send

Metric Ton KG G Pound L ML

Send

Send