Tert-butyl 3-(4-fluoroanilino)pyrrolidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 3-(4-fluoroanilino)pyrrolidine-1-carboxylate
CAS No.:853577-87-4
Molecular Formula:C₁₅H₂₁FN₂O₂
Molecular Weight:280.342
Hs Code.:
DSSTox Substance ID:DTXSID40459558
Mol file:853577-87-4.mol

Synonyms:853577-87-4;tert-butyl 3-(4-fluoroanilino)pyrrolidine-1-carboxylate;3-(4-FLUORO-PHENYLAMINO)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-Butyl 3-((4-fluorophenyl)amino)pyrrolidine-1-carboxylate;3-(4-fluorophenylamino)pyrrolidine-1-carboxylic acid tert-butyl ester;DTXSID40459558;AKOS017559200

Suppliers and Price of Tert-butyl 3-(4-fluoroanilino)pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-(4-Fluoro-phenylamino)-pyrrolidine-1-carboxylicacidtert-butylester 95
5g
$ 1833.00

American Custom Chemicals Corporation
3-(4-FLUORO-PHENYLAMINO)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 497.78

Total 2 raw suppliers

Chemical Property of Tert-butyl 3-(4-fluoroanilino)pyrrolidine-1-carboxylate

Chemical Property:

PSA：41.57000
LogP:3.25790
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:280.15870608
Heavy Atom Count:20
Complexity:335

Purity/Quality:

98% ^*data from raw suppliers

3-(4-Fluoro-phenylamino)-pyrrolidine-1-carboxylicacidtert-butylester 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(C1)NC2=CC=C(C=C2)F

Technology Process of Tert-butyl 3-(4-fluoroanilino)pyrrolidine-1-carboxylate

There total 1 articles about Tert-butyl 3-(4-fluoroanilino)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 460-00-4
1-Bromo-4-fluorobenzene

: 186550-13-0
3-amino-1-(t-butoxycarbonyl)pyrrolidine

: 853577-87-4
1-(tert-butoxycarbonyl)-3-(4-fluorophenylamino)pyrrolidine

Guidance literature:: With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; sodium t-butanolate; DavePhos; In xylene; at 130 ℃; for 24h;
DOI:10.1021/jo0487193