3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde

Base Information

• Chemical Name: 3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde
• CAS No.: 127484-27-9
• Molecular Formula: C₁₉H₂₄O₃
• Molecular Weight: 300.398
• Mol file: 127484-27-9.mol

Synonyms:3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde

Chemical Property of 3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde

There total 5 articles about 3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-<2-(Dimethoxymethyl)-6-methoxy>benzyl-2,4,4-trimethyl-3-(trimethylsilylmethyl)cyclohexenone (122873-94-3) → 3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde (127484-27-9)

Guidance literature:

With tin(IV) chloride; In dichloromethane; for 42h; Ambient temperature; also with TiCl₄;

DOI:10.1016/S0040-4020(01)91209-8

Reference yield:

(1R,8S)-3,8-Dimethoxy-11,14,14-trimethyl-tricyclo[8.3.1.02,7]tetradeca-2,4,6,10-tetraen-12-one → 3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde (127484-27-9)

Guidance literature:

With titanium tetrachloride; In dichloromethane; Ambient temperature;

DOI:10.1021/ja00203a039

Reference yield:

tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane (122844-99-9) → 3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde (127484-27-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / TiCl₄

2: TiCl₄ / CH₂Cl₂ / Ambient temperature

With titanium tetrachloride; In dichloromethane;

DOI:10.1021/ja00203a039

upstream raw materials:

5-<2-(Dimethoxymethyl)-6-methoxy>benzyl-2,4,4-trimethyl-3-(trimethylsilylmethyl)cyclohexenone

tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane

3-(tert-Butyl-dimethyl-silanyloxy)-5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,6,6-trimethyl-cyclohex-2-enone

3-(tert-Butyl-dimethyl-silanyloxy)-5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,6,6-trimethyl-1-trimethylsilanylmethyl-cyclohex-2-enol