tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane

Base Information

• Chemical Name: tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane
• CAS No.: 122844-99-9
• Molecular Formula: C₂₇H₄₄O₄Si
• Molecular Weight: 460.729
• Mol file: 122844-99-9.mol

Synonyms:tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane

Chemical Property of tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane

There total 2 articles about tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylsilylmethyllithium (1822-00-0) + 3-(tert-Butyl-dimethyl-silanyloxy)-5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,6,6-trimethyl-cyclohex-2-enone (122844-86-4) → tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane (122844-99-9)

Guidance literature:

With tert-butyl alcohol; Multistep reaction;

DOI:10.1021/ja00203a039

Reference yield:

3-(tert-Butyl-dimethyl-silanyloxy)-5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,6,6-trimethyl-1-trimethylsilanylmethyl-cyclohex-2-enol (127484-26-8) → tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane (122844-99-9)

Guidance literature:

With potassium tert-butylate;

DOI:10.1016/S0040-4020(01)91209-8

Reference yield:

tert-Butyl-[5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,4,4-trimethyl-3-methylene-cyclohex-1-enyloxy]-dimethyl-silane (122844-99-9) → 3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde (127484-27-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / TiCl₄

2: TiCl₄ / CH₂Cl₂ / Ambient temperature

With titanium tetrachloride; In dichloromethane;

DOI:10.1021/ja00203a039

upstream raw materials:

trimethylsilylmethyllithium

3-(tert-Butyl-dimethyl-silanyloxy)-5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,6,6-trimethyl-cyclohex-2-enone

3-(tert-Butyl-dimethyl-silanyloxy)-5-(2-dimethoxymethyl-6-methoxy-benzyl)-2,6,6-trimethyl-1-trimethylsilanylmethyl-cyclohex-2-enol

Downstream raw materials:

3-Methoxy-2-(2,2,3,4-tetramethyl-5-oxo-cyclohex-3-enylmethyl)-benzaldehyde