methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside

Base Information

• Chemical Name: methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside
• CAS No.: 493008-73-4
• Molecular Formula: C₈₉H₉₀O₁₈
• Molecular Weight: 1447.68
• Mol file: 493008-73-4.mol

Synonyms:methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside

Chemical Property of methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside

There total 5 articles about methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

methyl 2,4-di-O-benzyl-α-D-mannopyranoside (58341-67-6,67381-34-4,86172-91-0,86342-19-0,67381-29-7) + 1H-benzo[d][1,2,3]triazol-1-yl 2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranoside → methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside (493008-73-4)

Guidance literature:

methyl 2,4-di-O-benzyl-α-D-mannopyranoside; 1H-benzo[d][1,2,3]triazol-1-yl 2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranoside; In dichloromethane; at 0 ℃; for 0.25h; Inert atmosphere; Molecular sieve;

With trifluoromethylsulfonic anhydride; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/acs.joc.7b02027

Reference yield: 83.0%

methyl 2,4-di-O-benzyl-α-D-mannopyranoside (58341-67-6,67381-34-4,86172-91-0,86342-19-0,67381-29-7) + C43H44O9 → methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside (493008-73-4)

Guidance literature:

With C₃₃H₄₂AuN₂⁽¹⁺⁾*F₆Sb^(1-); In dichloromethane; at 25 ℃; for 0.25h; Reagent/catalyst; Molecular sieve; Inert atmosphere;

DOI:10.1039/d0cc03156a

Reference yield: 57.0%

methyl 2,4-di-O-benzyl-α-D-mannopyranoside (58341-67-6,67381-34-4,86172-91-0,86342-19-0,67381-29-7) + 3,4,6-tri-O-benzyl-β-D-mannopyranose 1,2-(pent-4-enyl orthobenzoate) (125392-62-3) → methyl 2,4-di-O-benzyl-3,6-di-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside (493008-73-4) + methyl 2,4-di-O-benzyl-6-O-(2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside (492455-07-9)

Guidance literature:

With N-iodo-succinimide; scandium tris(trifluoromethanesulfonate); In dichloromethane; at 0 ℃;

DOI:10.1016/j.carres.2006.09.022

upstream raw materials:

methyl 2,4-di-O-benzyl-α-D-mannopyranoside

ethyl 2-O-benzoyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside

n-pent-4-enyl 2-O-benzoyl-3,4,6-tri-O-benzyl-α-D-mannopyranoside

3,4,6-tri-O-benzyl-β-D-mannopyranose 1,2-(pent-4-enyl orthobenzoate)

Downstream raw materials:

methyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->3))-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl-(1->6))-2,4-di-O-benzyl-α-D-mannopyranoside