1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine

Base Information

Chemical Name:1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine
CAS No.:852227-96-4
Molecular Formula:C17H26 B N O2
Molecular Weight:287.21
Hs Code.:2934999090
European Community (EC) Number:690-008-6
DSSTox Substance ID:DTXSID20406883
Nikkaji Number:J3.611.166F
Wikidata:Q82212016
Mol file:852227-96-4.mol

Synonyms:852227-96-4;1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine;1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine;1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperidine;Piperidine,1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-;SCHEMBL539141;DTXSID20406883;OTOKWHGMHAAFRM-UHFFFAOYSA-N;(4-(PIPERIDIN-1-YL)PHENYL)BORONIC ACID PINACOL ESTER;1-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine;AMY30229;1,1'-[1,2-Ethanediylbis(oxy)];MFCD07368524;AKOS015950935;AB32036;AS-2426;CS-0061105;FT-0743236;J3.611.166F;A923567;J-504107;4-(1-PIPERIDINYL)BENZENEBORONIC ACID PINACOL ESTER;1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]piperidine;1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolane-2-yl)phenyl]piperidine

Suppliers and Price of 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine
10mg
$ 45.00

Matrix Scientific
1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperidine >95%
1g
$ 136.00

Matrix Scientific
1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperidine >95%
500mg
$ 101.00

Matrix Scientific
1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperidine >95%
5g
$ 498.00

Crysdot
1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine 97%
10g
$ 377.00

Chemenu
1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine 96%
250mg
$ 54.00

Chemenu
1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine 96%
1g
$ 135.00

Apolloscientific
1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperidine
5g
$ 340.00

Apolloscientific
1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperidine
1g
$ 124.00

Apolloscientific
1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-piperidine
500mg
$ 109.00

Total 15 raw suppliers

Chemical Property of 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine

Chemical Property:

Vapor Pressure:5.67E-07mmHg at 25°C
Melting Point:87 °C
Refractive Index:1.528
Boiling Point:411.2°C at 760 mmHg
PKA:5.55±0.20(Predicted)
Flash Point:202.5°C
PSA：21.70000
Density:1.04g/cm³
LogP:3.04110
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:287.2056592
Heavy Atom Count:21
Complexity:342

Purity/Quality:

97% ^*data from raw suppliers

1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)N3CCCCC3
Uses 4-(1-Piperidinyl)benzeneboronic acid pinacol ester is used as pharmaceutical intermediate.

Technology Process of 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine

There total 4 articles about 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 22148-20-5
N-(4-bromophenyl)piperidine

: 73183-34-3
bis(pinacol)diborane

: 852227-96-4
1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl)piperidine

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium hydrogencarbonate; In tetrahydrofuran; water; at 80 ℃; for 0.166667h; Microwave irradiation; Inert atmosphere;
DOI:10.1039/c3ob41982g

Reference yield: 62.0%

: 4280-36-8
(4-fluorophenyl)piperidine

: 73183-34-3
bis(pinacol)diborane

: 852227-96-4
1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl)piperidine

Guidance literature:: With tetramethylammonium fluoride; 2-mercaptopyridine sodium salt; In acetonitrile; at 30 - 35 ℃; for 24h; Irradiation; Inert atmosphere;
DOI:10.1016/j.chempr.2021.04.016