N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Base Information

Chemical Name:N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide
CAS No.:111986-19-7
Molecular Formula:C₁₉H₁₄ClN₅O₅
Molecular Weight:427.804
Hs Code.:

Synonyms:N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Suppliers and Price of N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

There total 4 articles about N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5843-48-1
2-Nitrobenzoyl isocyanate

: 111986-56-2
4-((5-chloropyrimidin-2-yl)oxy)-3-methylaniline

: 111986-19-7
N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Guidance literature:: In 1,4-dioxane; Ambient temperature;
DOI:10.1248/cpb.39.2308

Reference yield:

: 2835-96-3
4-amino-2-methylphenol

: 111986-19-7
N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Guidance literature:: Multi-step reaction with 2 steps

2: dioxane / Ambient temperature

In 1,4-dioxane;
DOI:10.1248/cpb.39.2308

Reference yield:

: 610-15-1
2-nitrobenzamide

: 111986-19-7
N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-nitrobenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 24 h / 0 °C / Reflux

2: 1,4-dioxane / 18 h / 20 °C

In 1,4-dioxane; toluene;
DOI:10.1016/j.chembiol.2019.04.009