4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide

Base Information

• Chemical Name: 4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide
• CAS No.: 1220704-67-5
• Molecular Formula: C₁₈H₁₈N₃OS₂*I
• Molecular Weight: 483.397
• Mol file: 1220704-67-5.mol

Synonyms:4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide

Chemical Property of 4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide

There total 1 articles about 4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C17H15N3OS2 (916348-89-5,916443-65-7,916443-69-1) + methyl iodide (74-88-4) → 4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide (1220704-67-5)

Guidance literature:

In acetonitrile; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2010.01.020

Reference yield: 95.0%

4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide (1220704-67-5) → 3-methylthiazolo[3,2-a]benzoimidazole (5268-73-5) + N-phenyl-S-methyl-thiocarbamate (13509-38-1)

Guidance literature:

With triethylamine; In acetonitrile; at 20 ℃; for 0.25h;

DOI:10.1016/j.tet.2010.01.020

Reference yield:

4-methyl-2-(methylthio)-3-(2-(3-phenylureido)phenyl)thiazol-3-iumiodide (1220704-67-5) + 2-(decylthio)-4-methyl-3-(2-(3-p-tolylureido)phenyl)thiazol-3-ium iodide (1220704-77-7) → 3-methylthiazolo[3,2-a]benzoimidazole (5268-73-5) + S-(decyl) p-tolylcarbamothioate (1220704-81-3) + N-phenyl-S-methyl-thiocarbamate (13509-38-1) + S-methyl N-(4-methylphenyl)thiocarbamate (61578-87-8) + S-(decyl) phenylcarbamothioate

Guidance literature:

With triethylamine; In methanol; at 20 ℃; for 0.5h;

DOI:10.1016/j.tet.2010.01.020

upstream raw materials:

C₁₇H₁₅N₃OS₂

methyl iodide

Downstream raw materials:

3-methylthiazolo[3,2-a]benzoimidazole

N-phenyl-S-methyl-thiocarbamate

S-(decyl) p-tolylcarbamothioate

S-methyl N-(4-methylphenyl)thiocarbamate