(R)-N-(1-(5-ethoxy-4-(4-nitrophenyl)oxazol-2-yl)-2,2-dimethylpropyl)-3-methoxyaniline

Base Information

Chemical Name:(R)-N-(1-(5-ethoxy-4-(4-nitrophenyl)oxazol-2-yl)-2,2-dimethylpropyl)-3-methoxyaniline
CAS No.:1408193-91-8
Molecular Formula:C₂₃H₂₇N₃O₅
Molecular Weight:425.484
Hs Code.:

Synonyms:(R)-N-(1-(5-ethoxy-4-(4-nitrophenyl)oxazol-2-yl)-2,2-dimethylpropyl)-3-methoxyaniline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-(1-(5-ethoxy-4-(4-nitrophenyl)oxazol-2-yl)-2,2-dimethylpropyl)-3-methoxyaniline

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Technology Process of (R)-N-(1-(5-ethoxy-4-(4-nitrophenyl)oxazol-2-yl)-2,2-dimethylpropyl)-3-methoxyaniline

There total 1 articles about (R)-N-(1-(5-ethoxy-4-(4-nitrophenyl)oxazol-2-yl)-2,2-dimethylpropyl)-3-methoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1268385-83-6
ethyl α-(p-nitrophenyl)-α-isocyanoacetate

: 536-90-3,918666-97-4
m-Anisidine

: 630-19-3
pivalaldehyde

: 1408193-91-8
(R)-N-(1-(5-ethoxy-4-(4-nitrophenyl)oxazol-2-yl)-2,2-dimethylpropyl)-3-methoxyaniline

Guidance literature:: m-Anisidine; pivalaldehyde; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere; Sealed tube;

ethyl α-(p-nitrophenyl)-α-isocyanoacetate; With (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; In dichloromethane; at -78 - -35 ℃; for 48h; Temperature; Solvent; enantioselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1002/chem.201202174