methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate

Base Information

• Chemical Name: methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate
• CAS No.: 1221407-55-1
• Molecular Formula: C₂₂H₂₅N₃O₇
• Molecular Weight: 443.456
• Mol file: 1221407-55-1.mol

Synonyms:methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate

Chemical Property of methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate

There total 1 articles about methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H21N3O6 + benzoic acid anhydride (93-97-0) → methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate (1221407-55-1)

Guidance literature:

In pyridine; dichloromethane;

DOI:10.1055/s-0029-1218566

Reference yield: 60.0%

methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate (1221407-55-1) → C22H24BrN3O7

Guidance literature:

With N-Bromosuccinimide; In water; dimethyl sulfoxide;

DOI:10.1055/s-0029-1218566

Reference yield: 46.0%

methyl 5-(benzoyloxy)-2-({1-[(tert-butoxycarbonyl)amino]but-3-en-1-yl})-6-hydroxypyrimidine-4-carboxylate (1221407-55-1) → trans-methyl 3-(benzoyloxy)-8-[(tert-butoxycarbonyl)amino]-6-(hydroxymethyl)-2-oxo-2,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-4-carboxylate + cis-methyl 3-(benzoyloxy)-8-[(tert-butoxycarbonyl)amino]-6-(hydroxymethyl)-2-oxo-2,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-4-carboxylate

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 37h; optical yield given as %de;

DOI:10.1055/s-0029-1218566

upstream raw materials:

benzoic acid anhydride