2-(4-methoxy-phenyl)-thiazole-4-carboxylic acid hydrochloride

Base Information

• Chemical Name: 2-(4-methoxy-phenyl)-thiazole-4-carboxylic acid hydrochloride
• CAS No.: 1023594-48-0
• Molecular Formula: C₁₁H₉NO₃S*ClH
• Molecular Weight: 271.724
• Mol file: 1023594-48-0.mol

Synonyms:2-(4-methoxy-phenyl)-thiazole-4-carboxylic acid hydrochloride

Chemical Property of 2-(4-methoxy-phenyl)-thiazole-4-carboxylic acid hydrochloride

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-(4-methoxy-phenyl)-thiazole-4-carboxylic acid hydrochloride

There total 1 articles about 2-(4-methoxy-phenyl)-thiazole-4-carboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(4-methoxyphenyl)thiazole-4-carboxylate (57677-79-9) → 2-(4-methoxy-phenyl)-thiazole-4-carboxylic acid hydrochloride (1023594-48-0)

Guidance literature:

ethyl 2-(4-methoxyphenyl)thiazole-4-carboxylate; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 15h;

With hydrogenchloride; water; In tetrahydrofuran;

Reference yield:

2-(4-methoxy-phenyl)-thiazole-4-carboxylic acid hydrochloride (1023594-48-0) + 1-[1,1-dimethylethoxycarbonyl]-4-(2-aminophenyl)piperazine (170017-74-0) → C26H30N4O4S (1029431-68-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 80 ℃; for 15h;

upstream raw materials:

ethyl 2-(4-methoxyphenyl)thiazole-4-carboxylate

Downstream raw materials:

C₂₆H₃₀N₄O₄S