C₃₀H₃₈NO₇PSi

Base Information

• Chemical Name: C₃₀H₃₈NO₇PSi
• CAS No.: 484068-42-0
• Molecular Formula: C₃₀H₃₈NO₇PSi
• Molecular Weight: 583.693
• Mol file: 484068-42-0.mol

Synonyms:C₃₀H₃₈NO₇PSi

Chemical Property of C₃₀H₃₈NO₇PSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₃₈NO₇PSi

There total 4 articles about C₃₀H₃₈NO₇PSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

diethyl chlorophosphate (814-49-3) + acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester (484068-40-8) → C30H38NO7PSi (484068-42-0)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h;

DOI:10.1021/ja028396x

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → C30H38NO7PSi (484068-42-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: N-hydroxylamine hydrochloride; triethylamine / CH₂Cl₂ / 3 h / 20 °C

1.2: 82 percent / triethylamine / CH₂Cl₂

2.1: 95 percent / Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

3.1: 95 percent / LHMDS / tetrahydrofuran / 0.5 h / -78 °C

With hydroxylamine hydrochloride; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja028396x

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → C30H38NO7PSi (484068-42-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: N-hydroxylamine hydrochloride; triethylamine / CH₂Cl₂ / 3 h / 20 °C

1.2: 82 percent / triethylamine / CH₂Cl₂

2.1: 95 percent / Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

3.1: 95 percent / LHMDS / tetrahydrofuran / 0.5 h / -78 °C

With hydroxylamine hydrochloride; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja028396x

upstream raw materials:

diethyl chlorophosphate

acetyl-tert-butyldiphenylsilyloxy-carbamic acid benzyl ester

benzyl chloroformate

tert-butylchlorodiphenylsilane