D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester

Base Information

Chemical Name:D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester
CAS No.:174961-32-1
Molecular Formula:C₂₁H₃₀N₂O₅
Molecular Weight:390.48
Hs Code.:

Synonyms:D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester

Suppliers and Price of D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester

There total 7 articles about D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 24424-99-5
di-tert-butyl dicarbonate

: (3-Amino-3-benzyl-2-oxo-piperidin-1-yl)-acetic acid ethyl ester; hydrochloride

: 174961-32-1
D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; water;
DOI:10.1016/S0960-894X(97)00446-0

Reference yield: 77.0%

: D,L-Boc-α-benzyl-NorVal(cyclo)Gly-O-ethyl ester

: 174961-32-1
D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester

Guidance literature:

Reference yield:

: 2480-93-5
Boc-Orn(Z)-OH

: 174961-32-1
D,L-3-(tert-Butoxycarbonyl)amino-3-benzyl-2-oxo-1-piperidineacetic acid, Ethyl ester

Guidance literature:: Multi-step reaction with 6 steps

2: 100 percent / HCl / 0 - 20 °C

3: 89 percent / Et₃N, MgSO₄ / CH₂Cl₂ / 0 - 20 °C

4: 89 percent / t-BuOK / tetrahydrofuran / Ambient temperature

5: HCl / H₂O / Ambient temperature

6: 77 percent / NaHCO₃ / tetrahydrofuran; H₂O

With hydrogenchloride; potassium tert-butylate; sodium hydrogencarbonate; magnesium sulfate; triethylamine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/S0960-894X(97)00446-0