ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate

Base Information

Chemical Name:ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate
CAS No.:1185016-32-3
Molecular Formula:C₁₈H₁₉N₅O₃
Molecular Weight:353.381
Hs Code.:

Synonyms:ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate

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Chemical Property of ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate

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Technology Process of ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate

There total 1 articles about ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 1-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)guanidine dinitrate

: 67751-14-8
ethyl 4-(dimethylamino)-2-oxo-3-butenoate

: 1185016-32-3
ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate

Guidance literature:: With potassium carbonate; In ethanol; at 170 ℃; for 0.5h; Microwave irradiation;

Reference yield: 88.0%

: 1185016-32-3
ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate

: cyclopropylmagnesium chloride

: 1185017-05-3
Dicyclopropyl-{2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidin-4-yl}-methanol

Guidance literature:: ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate; cyclopropylmagnesium chloride; In tetrahydrofuran; at 0 ℃;

With water; sodium carbonate; In tetrahydrofuran; Saturated solution;

Reference yield: 9.0%

: 1185016-32-3
ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate

: 2386-64-3
ethylmagnesium chloride

: 1185017-03-1
3-{2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidin-4-yl}-pentan-3-ol

: 1185017-04-2
C₁₈H₂₁N₅O₂

Guidance literature:: ethyl 2-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-pyrimidine-4-carboxylate; ethylmagnesium chloride; In tetrahydrofuran; at 0 ℃;

With water; sodium carbonate; In tetrahydrofuran; Saturated solution;